Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 12/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532673 | 0.84 | SOAT1 (0.44) | TXNRD1SOAT1 | |
| SCHEMBL9533205 | 0.84 | SOAT1 (0.44) | TXNRD1SOAT1 | |
| SCHEMBL9532500 | 0.83 | ALDH1A1 (0.43) | DCTPP1THRB | |
| SCHEMBL9532215 | 0.83 | ALDH1A1 (0.43) | DCTPP1THRB | |
| SCHEMBL9530748 | 0.83 | KDM4E (0.34) | DCTPP1THRBSOAT1 | |
| SCHEMBL9531331 | 0.82 | DCTPP1 (0.32) | DCTPP1SOAT1 | |
| SCHEMBL9530833 | 0.79 | CA12 (0.34) | THRBGSRTXNRD1SOAT1 | |
| SCHEMBL9533529 | 0.77 | CA12 (0.35) | THRBGSRTXNRD1SOAT1 | |
| SCHEMBL9534429 | 0.76 | CA12 (0.33) | GSRTXNRD1 | |
| SCHEMBL9535238 | 0.76 | GSR (0.36) | THRBGSRTXNRD1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | claimed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | claimed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | claimed |
| EP-0288196-B1 | Sulfonyldecahydro-8H-isoquino[2,1-g][1,6]naphthyridines, optical isomers thereof and related compounds | SYNTEX (U.S.A.) INC. (US) | 1993-07-28 | — | — | EP | disclosed |
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0524004-A1 | Decahydro-8H-isoquino[2,1-g][1,6]naphthyridine and decahydrobenzo[a]pyrrolo[2,3-e]quinolizine derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4956365-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS, ANTICOAGULANTS, ANTIDIABETIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4886798-A | Optical isomers of sulfonyldecahydro-8H-isoquino-(2,1-G)(1,6) naphthyridines and related compounds useful as α2 -blockers | SYNTEX (U.S.A.) INC. (US) | 1989-12-12 | — | — | US | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |