Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 4/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 3/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538648 | 0.81 | ALDH1A1 (0.53) | ALDH1A1ABCB1KDM1AMETAP2HSD17B10 | |
| SCHEMBL8111053 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ABCB1KDM1AMETAP2HSD17B10 | |
| SCHEMBL9534491 | 0.76 | LMNA (0.44) | ALDH1A1HSP90AA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7850997 | 0.74 | PDE10A (0.65) | ALDH1A1PDE10A | |
| SCHEMBL7840858 | 0.72 | PDE10A (0.54) | ALDH1A1ABCB1KDM1ANPC1RAB9A | |
| SCHEMBL7851014 | 0.72 | PDE10A (0.52) | ALDH1A1ABCB1KDM1AMETAP2NPC1 | |
| SCHEMBL7841650 | 0.71 | CKS1B (0.51) | ALDH1A1ABCB1KDM1AMETAP2HSD17B10 | |
| SCHEMBL7848799 | 0.71 | CKS1B (0.46) | ALDH1A1ABCB1KDM1AMETAP2HSD17B10 | |
| SCHEMBL10685876 | 0.70 | ALDH1A1 (0.51) | ALDH1A1ABCB1KDM1AMETAP2HSD17B10 | |
| SCHEMBL7840628 | 0.70 | ALDH1A1 (0.67) | ALDH1A1KDM1ANPC1RAB9APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5010195-A | From 5-alkoxy-1,2,4-triazolo(1,5-c)pyrimidine | THE DOW CHEMICAL COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | disclosed |