Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383037 | 0.75 | CACNA1B (0.36) | KDM4EHSD17B10PDE1CPDE2APDE5A | |
| SCHEMBL9532028 | 0.74 | PDE4B (0.51) | ALDH1A1PDE1CPDE2APDE5ACYP2C9 | |
| SCHEMBL27544295 | 0.71 | TSHR (0.46) | ALDH1A1KDM4EHSD17B10LMNAHTT | |
| SCHEMBL7376394 | 0.70 | KDM4E (0.44) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL416200 | 0.70 | EPHB3 (0.56) | NPC1RAB9ACAMKK1CAMKK2ALDH1A1 | |
| SCHEMBL7410687 | 0.69 | CACNA1B (0.61) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL8700129 | 0.69 | GAA (0.54) | ALDH1A1KDM4EHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL3034308 | 0.69 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL3034979 | 0.69 | CACNA1B (0.43) | ALDH1A1KDM4EHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL10642720 | 0.69 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270926-B1 | AGENTS PROMOTING THE ACTIVITY OF SOME ANTITUMOR AGENTS AND METHODS FOR THEIR PRODUCTION | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1993-03-17 | — | — | EP | claimed |
| EP-0270926-A2 | Agents promoting the activity of some antitumor agents and methods for their production | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1988-06-15 | — | — | EP | claimed |
| EP-0270926-B1 | AGENTS PROMOTING THE ACTIVITY OF SOME ANTITUMOR AGENTS AND METHODS FOR THEIR PRODUCTION | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4923871-A | ANTITUMOR | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-08 | — | — | US | disclosed |
| US-4923871-A | ANTITUMOR | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0270926-A2 | Agents promoting the activity of some antitumor agents and methods for their production | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1988-06-15 | — | — | EP | disclosed |
| EP-0270926-A2 | Agents promoting the activity of some antitumor agents and methods for their production | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1988-06-15 | — | — | EP | disclosed |