Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536365 | 0.91 | LMNA (0.57) | TSHRALDH1A1MAPTLMNAGLA | |
| SCHEMBL5242545 | 0.89 | ALDH1A1 (0.60) | TSHRALDH1A1GAAMAPTLMNA | |
| SCHEMBL9533615 | 0.84 | HSD17B10 (0.59) | ALDH1A1GAAMAPTLMNAL3MBTL1 | |
| SCHEMBL9537421 | 0.83 | TSHR (0.53) | TSHRALDH1A1GAAMAPTLMNA | |
| SCHEMBL9535614 | 0.83 | TSHR (0.53) | TSHRALDH1A1GAAMAPTLMNA | |
| SCHEMBL9535597 | 0.82 | NR1H4 (0.53) | TSHRPOLB | |
| SCHEMBL9533421 | 0.82 | SCN9A (0.49) | TSHRALDH1A1GAAMAPTLMNA | |
| SCHEMBL5242736 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNAGLAKMT2AGPBAR1 | |
| SCHEMBL9535220 | 0.80 | GHSR (0.51) | TSHRALDH1A1GAAMAPTLMNA | |
| SCHEMBL9535701 | 0.79 | KMT2A (0.54) | TSHRGAAPTGS2KMT2AGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |