Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 6/20 | 0.47 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537419 | 0.84 | UTS2R (0.44) | UTS2RMAPK1POLB | |
| SCHEMBL9535072 | 0.82 | UTS2R (0.47) | CYP2D6UTS2RMAPK1L3MBTL1HSD17B10 | |
| SCHEMBL9535041 | 0.78 | KDM4E (0.43) | UTS2RHSD17B10 | |
| SCHEMBL9535004 | 0.76 | PIK3CG (0.40) | UTS2RHSD17B10 | |
| SCHEMBL9534801 | 0.76 | PIK3CD (0.40) | UTS2RHSD17B10POLB | |
| SCHEMBL9534796 | 0.74 | LRRK2 (0.42) | MAPK1BRD4POLB | |
| SCHEMBL11102405 | 0.70 | UTS2R (0.44) | CYP2D6KAT2BATAD2UTS2RHRH3 | |
| SCHEMBL9972896 | 0.69 | PIK3CD (0.41) | HSD17B10 | |
| SCHEMBL9534736 | 0.68 | PIK3CD (0.43) | L3MBTL1HSD17B10 | |
| SCHEMBL9534851 | 0.68 | RXFP1 (0.49) | HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244352-B1 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0244352-A2 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |