Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535004 | 0.86 | PIK3CG (0.40) | KDM4EPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9534801 | 0.86 | PIK3CD (0.40) | KDM4EPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9534796 | 0.83 | LRRK2 (0.42) | KDM4EPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9535072 | 0.83 | UTS2R (0.47) | KDM4ESMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL9537419 | 0.80 | UTS2R (0.44) | SMN1; SMN2ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL9533783 | 0.78 | CYP2D6 (0.48) | UTS2RHSD17B10 | |
| SCHEMBL9972896 | 0.77 | PIK3CD (0.41) | KDM4ESMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL9534736 | 0.77 | PIK3CD (0.43) | KDM4EPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9534747 | 0.77 | PIK3CD (0.43) | KDM4EPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9534851 | 0.77 | RXFP1 (0.49) | KDM4EPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244352-B1 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | claimed |
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | claimed |
| EP-0244352-B1 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0244352-A2 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |