Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP9 | P55211 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535041 | 0.86 | KDM4E (0.43) | PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL9534801 | 0.84 | PIK3CD (0.40) | PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL9535072 | 0.82 | UTS2R (0.47) | PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL9534796 | 0.82 | LRRK2 (0.42) | PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL9534747 | 0.79 | PIK3CD (0.43) | PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL9537419 | 0.79 | UTS2R (0.44) | ALDH1A1MAPTLMNAKMT2ACASP7 | |
| SCHEMBL9533783 | 0.76 | CYP2D6 (0.48) | UTS2RHSD17B10 | |
| SCHEMBL9972896 | 0.76 | PIK3CD (0.41) | PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL9534736 | 0.76 | PIK3CD (0.43) | PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL9534851 | 0.76 | RXFP1 (0.49) | PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244352-B1 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0244352-A2 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |