Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.50 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23885424 | 0.84 | P2RX7 (0.66) | P2RX7FDPSHDAC6FGFR1FGFR4 | |
| SCHEMBL9534919 | 0.83 | P2RX7 (0.51) | P2RX7FDPSHDAC6FGFR1FGFR4 | |
| SCHEMBL983769 | 0.82 | ADORA2A (0.68) | FGFR1ADCY5ADORA2AADORA1 | |
| SCHEMBL9741153 | 0.81 | ADORA2A (0.66) | P2RX7FDPSHDAC6FGFR1FGFR4 | |
| SCHEMBL6805557 | 0.80 | P2RX7 (0.48) | P2RX7FDPSHDAC6FGFR1FGFR4 | |
| SCHEMBL21591519 | 0.79 | FGFR1 (0.51) | P2RX7FDPSHDAC6FGFR1FGFR4 | |
| SCHEMBL11596393 | 0.79 | FDPS (0.54) | P2RX7FDPSHDAC6FGFR1FGFR4 | |
| SCHEMBL30377761 | 0.78 | FLT4 (0.62) | HDAC6FGFR1ADCY5ADORA2AADORA1 | |
| SCHEMBL11596726 | 0.78 | ADORA2A (0.68) | P2RX7FDPSHDAC6FGFR1FGFR4 | |
| SCHEMBL15453238 | 0.78 | FDPS (0.52) | P2RX7FDPSHDAC6FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210077-A | Plant growth regulators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1993-05-11 | — | — | US | disclosed |