Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.51 |
| ▸ | PDCD1LG2 | Q9BQ51 | 10/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25C | P30307 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538604 | 0.87 | CD274 (0.45) | ALDH1A1HPGDKDM4ECD274PDCD1 | |
| SCHEMBL9535007 | 0.79 | MEN1 (0.50) | ALDH1A1HPGDKDM4ECD274PDCD1 | |
| SCHEMBL20718975 | 0.78 | CD274 (0.39) | ALDH1A1HPGDKDM4ECD274PDCD1 | |
| SCHEMBL9537485 | 0.78 | CD274 (0.47) | ALDH1A1HPGDKDM4ECD274PDCD1 | |
| SCHEMBL9537527 | 0.78 | CD274 (0.47) | ALDH1A1HPGDKDM4ECD274PDCD1 | |
| SCHEMBL697232 | 0.75 | CDC25B (0.63) | ALDH1A1HPGDKDM4ECDC25BCDC25A | |
| SCHEMBL11342375 | 0.73 | PRNP (0.47) | ALDH1A1HPGDKDM4ECDC25BCDC25A | |
| SCHEMBL9536899 | 0.73 | CDC25B (0.42) | ALDH1A1HPGDKDM4ECDC25BCDC25A | |
| SCHEMBL18070733 | 0.73 | CDC25B (0.49) | ALDH1A1HPGDKDM4ECDC25BCDC25A | |
| SCHEMBL27473924 | 0.71 | MAPT (0.47) | ALDH1A1HPGDKDM4ECD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |