Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533834 | 0.87 | ALDH1A1 (0.52) | CD274PDCD1CDC25BPDCD1LG2KDM4E | |
| SCHEMBL9533890 | 0.84 | CD274 (0.46) | CD274PDCD1CDC25BBTKPDCD1LG2 | |
| SCHEMBL9535007 | 0.81 | MEN1 (0.50) | CD274PDCD1CDC25BKDM4EALDH1A1 | |
| SCHEMBL9536294 | 0.79 | CD274 (0.42) | CD274PDCD1CDC25BBTKPDCD1LG2 | |
| SCHEMBL20718975 | 0.75 | CD274 (0.39) | CD274PDCD1PDCD1LG2KDM4EALDH1A1 | |
| SCHEMBL9535997 | 0.71 | CD274 (0.39) | CD274PDCD1BTKPDCD1LG2L3MBTL1 | |
| SCHEMBL18070733 | 0.69 | CDC25B (0.49) | CDC25BKDM4EALDH1A1HPGDGLA | |
| SCHEMBL9536313 | 0.69 | DHODH (0.42) | CD274PDCD1KDM4EALDH1A1HPGD | |
| SCHEMBL27552823 | 0.69 | KDM4E (0.50) | CDC25BKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL697232 | 0.69 | CDC25B (0.63) | CDC25BKDM4EALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |