Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214120 | 0.82 | CHRNA7 (0.51) | CHRNA7TACR1KMT2AMEN1TAAR1 | |
| SCHEMBL6012064 | 0.78 | CHRNA7 (0.68) | CHRNA7TACR1 | |
| SCHEMBL27870913 | 0.70 | CHRNB2 (0.48) | CHRNA7TACR1ACHEGBA1KMT2A | |
| SCHEMBL2539170 | 0.68 | CHRNA7 (1.00) | CHRNA7 | |
| SCHEMBL373002 | 0.68 | CHRNA7 (1.00) | CHRNA7 | |
| SCHEMBL2539169 | 0.68 | CHRNA7 (1.00) | CHRNA7 | |
| SCHEMBL27850987 | 0.67 | ACHE (0.47) | ACHECES2GBA1KMT2ACYP2A13 | |
| SCHEMBL9534022 | 0.67 | CYP2D6 (0.47) | TACR1ACHEGBA1KMT2ACYP2A13 | |
| SCHEMBL15692576 | 0.66 | ACHE (0.50) | ACHEKMT2ACCR3RAB9A | |
| Toluene SCHEMBL29131451 | 0.66 | LMNA (0.39) | CHRNA7TACR1ACHEGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550587-A1 | STEREOSELECTIVE PREPARATION OF ACID SENSITIVE AMIDES AND INTERMEDIATES USEFUL IN SAID PREPARATION | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992005146-A1 | STEREOSELECTIVE PREPARATION OF ACID SENSITIVE AMIDES AND INTERMEDIATES USEFUL IN SAID PREPARATION | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-04-02 | — | — | WO | claimed |