Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534950 | 0.89 | TSHR (0.49) | GPBAR1ALDH1A1LMNAKMT2ASCN9A | |
| SCHEMBL9532704 | 0.81 | TSHR (0.46) | GPBAR1ALDH1A1POLBLMNAKMT2A | |
| SCHEMBL9536365 | 0.81 | LMNA (0.57) | GPBAR1ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL5242736 | 0.81 | ALDH1A1 (0.58) | GPBAR1ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL9537784 | 0.79 | TSHR (0.46) | GPBAR1ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL9537042 | 0.76 | SMN1; SMN2 (0.54) | GPBAR1ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL9535763 | 0.74 | KMT2A (0.58) | GPBAR1ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL9536336 | 0.73 | SCN9A (0.54) | ALDH1A1LMNASMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27324747 | 0.72 | LMNA (0.52) | GPBAR1ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL7184918 | 0.72 | TSHR (0.82) | GPBAR1ALDH1A1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |