Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536259 | 0.86 | PTGS2 (0.50) | SCN9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9537484 | 0.84 | LMNA (0.52) | KMT2ALMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9536365 | 0.82 | LMNA (0.57) | SCN9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5242736 | 0.82 | ALDH1A1 (0.58) | SCN9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9534217 | 0.80 | TP53 (0.51) | SCN9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9537042 | 0.78 | SMN1; SMN2 (0.54) | SCN9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9535763 | 0.76 | KMT2A (0.58) | SCN9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9535614 | 0.75 | TSHR (0.53) | SCN9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL12584906 | 0.75 | SCN9A (0.67) | SCN9AKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11893412 | 0.74 | ALDH1A1 (0.72) | KMT2ALMNASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |