Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998371 | 0.80 | HRH3 (0.39) | — | |
| SCHEMBL7706424 | 0.78 | HRH3 (0.42) | — | |
| SCHEMBL5946046 | 0.77 | ALDH1A1 (0.37) | — | |
| SCHEMBL5540209 | 0.75 | POLB (0.45) | — | |
| SCHEMBL290317 | 0.75 | GLA (0.42) | — | |
| SCHEMBL7658764 | 0.71 | HRH3 (0.38) | KDM1AGAAARG1ARG2 | |
| SCHEMBL10855530 | 0.71 | GAA (0.34) | KDM1AGAAARG1ARG2 | |
| SCHEMBL259387 | 0.71 | MAPK1 (0.40) | KDM1AGAA | |
| SCHEMBL9534069 | 0.71 | KDM1A (0.32) | KDM1AGAAARG1ARG2 | |
| SCHEMBL2652115 | 0.69 | DRD3 (0.51) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| US-5032606-A | Novel fluorinated resorcinol ethers and their use as anti-allergics and anti-inflammatories | CIBA-GEIGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0222961-B1 | RESORCINOL ETHERS | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | disclosed |
| US-4863942-A | Novel resorcinol ethers and anti-inflammatory and anti-allergic use thereof | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4820726-A | Oxaloamino substituted fluorinated resorcinol ethers and anti-allergic and anti-inflammatory use thereof | CIBA-GEIGY CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0165897-B1 | RESORCIN ETHERS | CIBA-GEIGY AG (CH) | 1989-03-15 | — | — | EP | disclosed |
| US-4670604-A | Novel fluorinated resorcinol ethers | CIBA-GEIGY CORPORATION (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0222961-A1 | Resorcinol ethers | CIBA-GEIGY AG (CH) | 1987-05-27 | — | — | EP | disclosed |
| EP-0165897-A2 | Resorcin ethers | CIBA-GEIGY AG (CH) | 1985-12-27 | — | — | EP | disclosed |
| EP-0089926-A2 | Pharmaceutical preparations of tetracycles containing nitrogen, and compounds of this type | CIBA-GEIGY AG (CH) | 1983-09-28 | — | — | EP | disclosed |