Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481977 | 0.82 | SLC6A4 (0.39) | DRD2SLC6A4HTR1AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9521526 | 0.81 | SLC6A4 (0.52) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9669426 | 0.81 | SLC6A4 (0.39) | DRD2SLC6A4HTR1AALDH1A1LMNA | |
| SCHEMBL9535109 | 0.79 | DRD2 (0.46) | DRD2SLC6A4HTR1AALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL9520231 | 0.73 | SLC6A4 (0.47) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL9520310 | 0.72 | DRD2 (0.55) | DRD2SLC6A4HTR1AALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL9521365 | 0.72 | DRD2 (0.55) | DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9520957 | 0.71 | SLC6A4 (0.47) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9482697 | 0.71 | HTR1A (0.48) | DRD2SLC6A4HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL9520421 | 0.71 | DRD2 (0.51) | DRD2SLC6A4HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396620-B1 | AMINOMETHYL-CHROMAN AND -THIOCHROMAN COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-08-11 | — | — | EP | claimed |