Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9521365 | 0.83 | DRD2 (0.55) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9520310 | 0.83 | DRD2 (0.55) | DRD2DRD4DRD3TSHRALDH1A1 | |
| SCHEMBL9482697 | 0.82 | HTR1A (0.48) | DRD2DRD4DRD3ADAM17HTR1A | |
| Hydrochloric Acid SCHEMBL9520421 | 0.82 | DRD2 (0.51) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL9464480 | 0.81 | HTR1A (0.47) | DRD2DRD4DRD3ADAM17HTR1A | |
| SCHEMBL9531339 | 0.81 | HTR1A (0.57) | ALDH1A1HTR1ASLC6A4 | |
| SCHEMBL9533763 | 0.81 | HTR1A (0.43) | DRD2DRD3HTR1ASLC6A4 | |
| SCHEMBL9534158 | 0.79 | DRD2 (0.38) | DRD2DRD4ALDH1A1HTR1ASLC6A4 | |
| SCHEMBL9523624 | 0.78 | DRD2 (0.47) | DRD2DRD4DRD3ADAM17TSHR | |
| Hydrochloric Acid SCHEMBL9521463 | 0.78 | DRD2 (0.48) | DRD2DRD4DRD3ADAM17MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396620-B1 | AMINOMETHYL-CHROMAN AND -THIOCHROMAN COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-08-11 | — | — | EP | claimed |