Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.59 |
| ▸ | PDCD1 | Q15116 | 9/20 | 0.59 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESD | P10768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536771 | 0.82 | MAOB (0.61) | CD274PDCD1MAOBMEN1MAPT | |
| SCHEMBL9536506 | 0.81 | CD274 (0.54) | CD274PDCD1MAOB | |
| SCHEMBL9533962 | 0.78 | MAOB (0.62) | CD274PDCD1MAOBMEN1LMNA | |
| SCHEMBL9532880 | 0.78 | MAOB (0.50) | CD274PDCD1MAOB | |
| SCHEMBL9533843 | 0.77 | MAOB (0.49) | CD274PDCD1MAOBMEN1KMT2A | |
| SCHEMBL9534735 | 0.76 | MAOB (0.63) | CD274PDCD1MAOBMAPTKMT2A | |
| SCHEMBL10381309 | 0.76 | MAOB (0.60) | CD274PDCD1MAOBMEN1LMNA | |
| SCHEMBL10382659 | 0.74 | MAOB (0.64) | MAOBMEN1MAPTKMT2A | |
| SCHEMBL22908687 | 0.74 | CD274 (1.00) | CD274PDCD1MEN1LMNAMAPT | |
| SCHEMBL10381326 | 0.73 | MAOB (0.60) | CD274PDCD1MAOBMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |