Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 7/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535163 | 0.81 | MAOB (0.47) | MAOBCD274PDCD1BRD4 | |
| SCHEMBL9536771 | 0.79 | MAOB (0.61) | MAOBCD274PDCD1 | |
| SCHEMBL9531404 | 0.79 | MAOB (0.45) | MAOBCD274PDCD1BRD4 | |
| SCHEMBL9536506 | 0.79 | CD274 (0.54) | MAOBCD274PDCD1BRD4 | |
| SCHEMBL9534473 | 0.78 | CD274 (0.59) | MAOBCD274PDCD1 | |
| SCHEMBL9533962 | 0.77 | MAOB (0.62) | MAOBCD274PDCD1 | |
| SCHEMBL10382659 | 0.76 | MAOB (0.64) | MAOB | |
| SCHEMBL9534735 | 0.75 | MAOB (0.63) | MAOBCD274PDCD1 | |
| SCHEMBL18334526 | 0.74 | PDCD1 (0.59) | CD274PDCD1BRD4ALOX5 | |
| SCHEMBL9533843 | 0.73 | MAOB (0.49) | MAOBCD274PDCD1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |