Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057353 | 0.89 | ALDH1A1 (0.30) | — | |
| SCHEMBL9534530 | 0.84 | CA2 (0.47) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8950300 | 0.78 | CA2 (0.50) | CA2CA4CA12CA1CA6 | |
| SCHEMBL9057400 | 0.76 | PSEN1 (0.34) | — | |
| SCHEMBL9057403 | 0.76 | PSEN1 (0.34) | — | |
| SCHEMBL8868900 | 0.73 | CA2 (0.57) | CA2CA4CA12CA1CA6 | |
| SCHEMBL8871391 | 0.73 | CA2 (0.57) | CA2CA4CA12CA1CA6 | |
| SCHEMBL9062550 | 0.71 | CA2 (0.34) | CA2CA4CA12CA1CA6 | |
| SCHEMBL9115525 | 0.70 | DUT (0.32) | — | |
| SCHEMBL9114356 | 0.70 | CA2 (0.37) | CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019981-A1 | THIENOTHIAZINE SULFONAMIDE DERIVATIVES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1995-07-27 | — | — | WO | disclosed |