Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533695 | 0.94 | NR1H4 (0.46) | GHSRALDH1A1NR1H4 | |
| SCHEMBL9538135 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2SCN9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL9536417 | 0.86 | GPBAR1 (0.46) | L3MBTL1ALDH1A1NR1H4 | |
| SCHEMBL9533125 | 0.81 | KMT2A (0.48) | SMN1; SMN2SCN9AKMT2AMEN1GHSR | |
| SCHEMBL9535349 | 0.81 | SCN5A (0.46) | SMN1; SMN2SCN9AGHSRALDH1A1SCN5A | |
| SCHEMBL9535030 | 0.80 | GHSR (0.46) | SMN1; SMN2SCN9AGHSRALDH1A1SCN5A | |
| SCHEMBL9535597 | 0.73 | NR1H4 (0.53) | GHSRPOLBNR1H4 | |
| SCHEMBL9533158 | 0.72 | SMN1; SMN2 (0.52) | SMN1; SMN2SCN9AKMT2AL3MBTL1NPC1 | |
| SCHEMBL9536660 | 0.71 | GPBAR1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL9534075 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2SCN9AKMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |