Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535030 | 0.89 | GHSR (0.46) | ALDH1A1MGLL | |
| SCHEMBL9538135 | 0.85 | SMN1; SMN2 (0.48) | ALDH1A1MAPT | |
| SCHEMBL9536417 | 0.85 | GPBAR1 (0.46) | GPBAR1ALDH1A1 | |
| SCHEMBL9533601 | 0.83 | MAPT (0.51) | ALDH1A1MAPT | |
| SCHEMBL9535349 | 0.82 | SCN5A (0.46) | ALDH1A1MGLL | |
| SCHEMBL9533695 | 0.74 | NR1H4 (0.46) | ALDH1A1 | |
| SCHEMBL9538504 | 0.72 | GPBAR1 (0.53) | GPBAR1ALDH1A1MAPT | |
| SCHEMBL9534540 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1MAPT | |
| SCHEMBL9534075 | 0.70 | SMN1; SMN2 (0.43) | ALDH1A1MAPT | |
| SCHEMBL9535220 | 0.69 | GHSR (0.51) | GPBAR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |