Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535030 | 0.93 | GHSR (0.46) | SCN5ASCN9AALDH1A1GHSREPHX2 | |
| SCHEMBL9538135 | 0.87 | SMN1; SMN2 (0.48) | SCN5ASCN9AALDH1A1GHSRLMNA | |
| SCHEMBL9533695 | 0.86 | NR1H4 (0.46) | ALDH1A1GHSR | |
| SCHEMBL9422725 | 0.82 | GHSR (0.59) | ALDH1A1GHSRSMN1; SMN2 | |
| SCHEMBL9536660 | 0.82 | GPBAR1 (0.47) | ALDH1A1MGLL | |
| SCHEMBL9534540 | 0.81 | SMN1; SMN2 (0.47) | SCN5ASCN9AALDH1A1GHSRSMN1; SMN2 | |
| SCHEMBL9533421 | 0.80 | SCN9A (0.49) | SCN5ASCN9AALDH1A1GHSRLMNA | |
| SCHEMBL9538122 | 0.79 | SCN9A (0.50) | SCN5ASCN9AALDH1A1GHSR | |
| SCHEMBL9533943 | 0.78 | GHSR (0.54) | SCN5ASCN9AGHSR | |
| SCHEMBL9536053 | 0.75 | SCN9A (0.53) | SCN5ASCN9AALDH1A1GHSRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |