Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534033 | 0.87 | PKM (0.50) | CYP1A2TDP1PKMKDM4ELMNA | |
| SCHEMBL9533900 | 0.84 | KDM4E (0.43) | CYP1A2TDP1PKMKDM4EGAA | |
| SCHEMBL9533415 | 0.81 | PKM (0.41) | CYP1A2TDP1PKMKDM4ELMNA | |
| SCHEMBL9533910 | 0.81 | PKM (0.46) | CYP1A2TDP1PKMKDM4EMAPT | |
| SCHEMBL9770762 | 0.80 | CYP1A2 (0.43) | CYP1A2TDP1PKMKDM4EGAA | |
| SCHEMBL9535141 | 0.80 | CYP1A2 (0.50) | CYP1A2TDP1PKMGAALMNA | |
| SCHEMBL9534833 | 0.77 | CYP1A2 (0.50) | CYP1A2TDP1PKMGAALMNA | |
| SCHEMBL9534383 | 0.77 | TDP1 (0.50) | CYP1A2TDP1PKMKDM4EGAA | |
| SCHEMBL9534961 | 0.76 | CYP1A2 (0.43) | CYP1A2TDP1PKMKDM4EGAA | |
| SCHEMBL9532954 | 0.76 | SMN1; SMN2 (0.41) | CYP1A2PKMGAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |