Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FRK | P42685 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534833 | 0.82 | CYP1A2 (0.50) | CYP1A2TDP1PARP1GAAPKM | |
| SCHEMBL9535141 | 0.82 | CYP1A2 (0.50) | CYP1A2TDP1PARP1GAAPKM | |
| SCHEMBL9534383 | 0.82 | TDP1 (0.50) | CYP1A2TDP1GAAPKMSMN1; SMN2 | |
| SCHEMBL10696638 | 0.82 | CYP1A2 (0.40) | CYP1A2TDP1GAAPKMSMN1; SMN2 | |
| SCHEMBL9534657 | 0.80 | CYP1A2 (0.42) | CYP1A2TDP1GAAPKMSMN1; SMN2 | |
| SCHEMBL9534033 | 0.79 | PKM (0.50) | CYP1A2TDP1PKMSMN1; SMN2HSD17B10 | |
| SCHEMBL9534961 | 0.79 | CYP1A2 (0.43) | CYP1A2TDP1PTGS2GAAPKM | |
| SCHEMBL9770496 | 0.77 | CYP1A2 (0.43) | CYP1A2TDP1GAAPKMSMN1; SMN2 | |
| SCHEMBL9533900 | 0.76 | KDM4E (0.43) | CYP1A2TDP1GAAPKMHSD17B10 | |
| SCHEMBL9534194 | 0.76 | DHFR (0.45) | CYP1A2TDP1PTGS2GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110862385-B | Application of copper catalyst in preparation of thiazoloquinazolinone derivative through reaction of 1-thiazolylindole compound and tert-butyl nitrite | 苏州大学 | 2020-12-08 | — | — | CN | disclosed |
| CN-110862385-A | Application of copper catalyst in preparation of thiazoloquinazolinone derivative through reaction of 1-thiazolylindole compound and tert-butyl nitrite | 苏州大学 | 2020-03-06 | — | — | CN | disclosed |
| CN-108774248-B | Method for preparing thiazoloquinazolinone derivative | 苏州大学 | 2020-01-14 | — | — | CN | disclosed |
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |
| EP-0078003-B1 | THIAZOLO (2,3-B)-QUINAZOLONES AND PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1986-03-05 | — | — | EP | disclosed |
| US-4486221-A | POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1984-12-04 | — | — | US | disclosed |