Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770762 | 0.82 | CYP1A2 (0.43) | CYP1A2SMN1; SMN2PKMRAB9ATSHR | |
| SCHEMBL9535141 | 0.82 | CYP1A2 (0.50) | CYP1A2SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL9534383 | 0.82 | TDP1 (0.50) | CYP1A2SMN1; SMN2PKML3MBTL1ALDH1A1 | |
| SCHEMBL10696638 | 0.79 | CYP1A2 (0.40) | CYP1A2SMN1; SMN2PKML3MBTL1ALDH1A1 | |
| SCHEMBL9534033 | 0.79 | PKM (0.50) | CYP1A2SMN1; SMN2PKMTSHRL3MBTL1 | |
| SCHEMBL9534961 | 0.79 | CYP1A2 (0.43) | CYP1A2SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL9532712 | 0.79 | CYP1A2 (0.53) | CYP1A2SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL9534103 | 0.78 | SMN1; SMN2 (0.41) | CYP1A2SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL9532954 | 0.78 | SMN1; SMN2 (0.41) | CYP1A2SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL9534657 | 0.77 | CYP1A2 (0.42) | CYP1A2SMN1; SMN2PKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |