Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536397 | 0.89 | TOP2A (0.47) | KCNH2KDM4EATMTOP2ATOP2B | |
| SCHEMBL9537262 | 0.78 | TOP2A (0.51) | KCNH2KDM4ETOP2ATOP2BALDH1A1 | |
| SCHEMBL9535368 | 0.76 | TOP2A (0.51) | KCNH2KDM4ETOP2ATOP2BALDH1A1 | |
| SCHEMBL9543963 | 0.76 | KDM4E (0.32) | KDM4ETOP2ATOP2BALDH1A1HPGD | |
| SCHEMBL8741054 | 0.75 | ADRB2 (0.51) | ADRB2KCNH2KDM4EATMTOP2A | |
| SCHEMBL9572064 | 0.73 | ADRB2 (0.49) | ADRB2KCNH2KDM4ETOP2ATOP2B | |
| SCHEMBL12818938 | 0.72 | ADRB2 (0.42) | ADRB2KCNH2KDM4EATMTOP2A | |
| SCHEMBL10374530 | 0.71 | KCNH2 (0.51) | KCNH2KDM4EATMTOP2ATOP2B | |
| SCHEMBL10687624 | 0.71 | KCNH2 (0.51) | KCNH2KDM4EATMTOP2ATOP2B | |
| SCHEMBL9388005 | 0.71 | ALDH1A1 (0.55) | KCNH2KDM4EATMTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549857-A1 | Antibacterial quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550019-A2 | Novel quinolone carboxylic acid derivatives and processes for preparing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |