SCHEMBL9534714

SCHEMBL9534714

O=C(N[C@H]1[C@H]2CC[C@H](C2)[C@@H]1C(=O)O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
GAA P10253 1/20 0.56
CPB1 P15086 2/20 0.52
TSHR P16473 1/20 0.51
TAAR1 Q96RJ0 1/20 0.49
EPHX1 P07099 1/20 0.48
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
CTSK P43235 1/20 0.46
TLR4 O00206 1/20 0.46
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19213028 0.89 CPB1 (0.61) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL9537538 0.89 CPB1 (0.61) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL9537540 0.89 CPB1 (0.61) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL25186674 0.87 ALDH1A1 (0.51) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL25183342 0.87 ALDH1A1 (0.51) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL29739725 0.85 ALDH1A1 (0.54) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL29739737 0.85 ALDH1A1 (0.54) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL395240 0.83 CPB1 (0.60) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL29739843 0.83 CPB1 (0.54) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL394782 0.83 CPB1 (0.60) ALDH1A1GAACPB1TSHREPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0352083-B1 Alkenyltetrazole derivatives, their preparation and use SHIONOGI & CO (JP) 1993-11-24 EP disclosed
EP-0384747-A1 Pharmaceutical or veterinary preparations of substituted hexenoic acid derivatives SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-08-29 EP disclosed
US-4916231-A THROMBOXANE A2 RECPTOR ANTAGONISTS SHIONOGI & CO., LTD. (JP) 1990-04-10 US disclosed
EP-0352083-A2 Alkenyltetrazole derivatives, their preparation and use SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-01-24 EP disclosed