SCHEMBL9537538

SCHEMBL9537538

COC(=O)[C@H]1[C@@H]2CC[C@@H](C2)[C@@H]1NC(=O)OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CPB1 P15086 2/20 0.61
ALDH1A1 P00352 3/20 0.55
CYP2C9 P11712 3/20 0.55
CYP2C19 P33261 3/20 0.55
CYP1A2 P05177 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
GAA P10253 1/20 0.50
TSHR P16473 2/20 0.48
POLB P06746 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
SLC6A3 Q01959 1/20 0.46
EPHX1 P07099 1/20 0.45
LMNA P02545 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ACHE P22303 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19213028 1.00 CPB1 (0.61) CPB1ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL9537540 1.00 CPB1 (0.61) CPB1ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL394782 0.93 CPB1 (0.60) CPB1ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL395240 0.93 CPB1 (0.60) CPB1ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL394783 0.93 CPB1 (0.60) CPB1ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL9534714 0.89 ALDH1A1 (0.56) CPB1ALDH1A1CYP1A2GAATSHR
SCHEMBL16272925 0.83 CPB1 (0.46) CPB1ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL29739843 0.82 CPB1 (0.54) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL29739718 0.82 CPB1 (0.54) CPB1ALDH1A1GAATSHREPHX1
SCHEMBL29739737 0.82 ALDH1A1 (0.54) CPB1ALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0352083-B1 Alkenyltetrazole derivatives, their preparation and use SHIONOGI & CO (JP) 1993-11-24 EP disclosed
EP-0384747-A1 Pharmaceutical or veterinary preparations of substituted hexenoic acid derivatives SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-08-29 EP disclosed
US-4916231-A THROMBOXANE A2 RECPTOR ANTAGONISTS SHIONOGI & CO., LTD. (JP) 1990-04-10 US disclosed
EP-0352083-A2 Alkenyltetrazole derivatives, their preparation and use SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-01-24 EP disclosed