Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPX4 | P36969 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378405 | 0.75 | — | — | |
| SCHEMBL4550633 | 0.74 | CYP1A2 (0.52) | GPX4 | |
| SCHEMBL24438361 | 0.73 | ALDH1A1 (0.48) | GPX4 | |
| SCHEMBL8722765 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL8432009 | 0.73 | ALDH1A1 (0.48) | GPX4 | |
| SCHEMBL6969800 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL1591122 | 0.71 | HTR1A (0.39) | — | |
| SCHEMBL1307068 | 0.71 | CYP1A2 (0.54) | — | |
| SCHEMBL209742 | 0.71 | — | — | |
| SCHEMBL9532761 | 0.70 | GPX4 (0.39) | GPX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |