Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437452 | 0.86 | L3MBTL1 (0.50) | L3MBTL1SLC13A5MAPK1LMNAALDH1A1 | |
| SCHEMBL12948866 | 0.79 | SLC13A5 (0.52) | L3MBTL1SLC13A5MAPK1LMNAALDH1A1 | |
| SCHEMBL10752180 | 0.78 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1HTTMAPTTSHR | |
| SCHEMBL24107506 | 0.78 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL3418880 | 0.76 | KMT2A (0.58) | L3MBTL1SLC13A5MAPK1LMNAALDH1A1 | |
| SCHEMBL13034142 | 0.76 | L3MBTL1 (0.54) | L3MBTL1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL21155351 | 0.75 | ALDH1A1 (0.42) | L3MBTL1MAPK1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27486669 | 0.75 | MEN1 (0.51) | L3MBTL1LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9828121 | 0.75 | MEN1 (0.47) | L3MBTL1LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4067440 | 0.75 | MAPT (0.46) | MAPK1LMNAALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382629-B1 | Aminoalkoxyphenyl derivatives, process for their preparation and compositions containing them | SANOFI ELF (FR) | 1993-11-24 | — | — | EP | disclosed |
| EP-0382629-A1 | Aminoalkoxyphenyl derivatives, process for their preparation and compositions containing them | ELF SANOFI (FR) | 1990-08-16 | — | — | EP | disclosed |