Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535360 | 0.87 | HRH1 (0.54) | SLC6A9HRH1TP53KCNH2MAPT | |
| SCHEMBL9536097 | 0.87 | SLC6A9 (0.45) | SLC6A9HRH1TP53KCNH2MAPT | |
| SCHEMBL10382570 | 0.86 | SLC6A9 (0.44) | SLC6A9HRH1TP53KCNH2MAPT | |
| Oxalic Acid SCHEMBL9539814 | 0.85 | HRH1 (0.47) | SLC6A9HRH1TP53KCNH2MAPT | |
| Oxalic Acid SCHEMBL9539822 | 0.85 | HRH1 (0.47) | SLC6A9HRH1TP53KCNH2MAPT | |
| SCHEMBL10382581 | 0.85 | SLC6A9 (0.36) | SLC6A9HRH1TP53KCNH2MAPT | |
| SCHEMBL9535297 | 0.85 | SLC6A9 (0.47) | SLC6A9HRH1TP53KDM4EMEN1 | |
| SCHEMBL9535868 | 0.84 | SLC6A9 (0.44) | SLC6A9HRH1KCNH2MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10384124 | 0.83 | SLC6A9 (0.44) | SLC6A9HRH1KCNH2MAPTKDM4E | |
| SCHEMBL9686900 | 0.82 | SLC6A9 (0.60) | SLC6A9TP53KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |