Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10384124 | 0.99 | SLC6A9 (0.44) | SLC6A9PDE5AKCNH2MAPTKDM4E | |
| SCHEMBL9535360 | 0.89 | HRH1 (0.54) | SLC6A9KCNH2MAPTHRH1CHRM1 | |
| SCHEMBL9536097 | 0.89 | SLC6A9 (0.45) | SLC6A9KCNH2MAPTKDM4EHRH1 | |
| SCHEMBL10383260 | 0.88 | TP53 (0.46) | SLC6A9PDE5AKCNH2MAPTKDM4E | |
| SCHEMBL9536525 | 0.88 | MAPT (0.42) | KCNH2MAPTHRH1RETCHRM1 | |
| SCHEMBL9538395 | 0.88 | MAPT (0.39) | SLC6A9KCNH2MAPTRET | |
| Oxalic Acid SCHEMBL9539814 | 0.87 | HRH1 (0.47) | SLC6A9KCNH2MAPTKDM4EHRH1 | |
| SCHEMBL9537031 | 0.87 | SLC6A9 (0.42) | SLC6A9KCNH2MAPTKDM4EHRH1 | |
| Oxalic Acid SCHEMBL9539822 | 0.87 | HRH1 (0.47) | SLC6A9KCNH2MAPTKDM4EHRH1 | |
| SCHEMBL9536529 | 0.87 | NOS2 (0.55) | MAPTKDM4ENOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | claimed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | claimed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |