Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10390191 | 1.00 | CCR6 (0.36) | CCR6PDPK1MAOAMAOBBCHE | |
| SCHEMBL9805064 | 0.86 | ADRA2A (0.32) | PDPK1ADRA2BADRA2CALDH1A1 | |
| SCHEMBL9532805 | 0.86 | ADRA2A (0.32) | PDPK1ADRA2BADRA2CALDH1A1 | |
| SCHEMBL9532810 | 0.86 | ADRA2A (0.32) | PDPK1ADRA2BADRA2CALDH1A1 | |
| SCHEMBL2583993 | 0.75 | PDPK1 (0.53) | CCR6PDPK1HTR2AHTR2CHTR2B | |
| SCHEMBL9531715 | 0.67 | ALDH1A1 (0.32) | CCR6ALDH1A1 | |
| SCHEMBL2400566 | 0.65 | PDPK1 (0.41) | PDPK1MAOAMAOBHTR2AHTR2C | |
| SCHEMBL8611199 | 0.65 | HTR2A (0.44) | PDPK1BCHEHTR2AHTR2CHTR2B | |
| SCHEMBL9493200 | 0.65 | PDPK1 (0.43) | PDPK1MAOBHTR2A | |
| SCHEMBL29447996 | 0.65 | HTR2A (0.44) | PDPK1BCHEHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |