Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PRMT7 | Q9NVM4 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535481 | 0.91 | TTR (0.57) | TTRNPC1RAB9ABCAT1AHR | |
| SCHEMBL11749377 | 0.90 | TTR (0.63) | TTRNPC1RAB9AAKR1B1KDM4E | |
| SCHEMBL28414324 | 0.84 | TTR (0.64) | TTRNPC1RAB9AAKR1B1KDM4E | |
| SCHEMBL11841224 | 0.83 | TTR (0.50) | TTRAHRLMNAHTTKDM4E | |
| SCHEMBL1783797 | 0.82 | TTR (0.74) | TTRNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL9691287 | 0.81 | TTR (0.51) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL71110 | 0.80 | TTR (0.68) | TTRNPC1RAB9ABCAT1STS | |
| SCHEMBL11550016 | 0.79 | ALDH1A1 (0.54) | TTRNPC1RAB9ABCAT1STS | |
| SCHEMBL10788381 | 0.79 | TTR (0.61) | TTRNPC1RAB9AAHRLMNA | |
| SCHEMBL2043165 | 0.78 | NPC1 (0.69) | TTRNPC1RAB9APRMT7PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3953602-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-04-27 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |