Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | USP10 | Q14694 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536466 | 0.87 | USP7 (0.48) | L3MBTL1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9537385 | 0.84 | L3MBTL1 (0.55) | L3MBTL1POLBSMN1; SMN2KMT2ALMNA | |
| Diethylamine SCHEMBL9535505 | 0.84 | USP7 (0.46) | L3MBTL1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL18376382 | 0.82 | MAPT (0.66) | L3MBTL1PRMT5WDR77POLBMAPT | |
| Hydrochloric Acid SCHEMBL18763571 | 0.82 | MAPT (0.65) | L3MBTL1PRMT5WDR77POLBMAPT | |
| SCHEMBL9537206 | 0.81 | USP7 (0.51) | L3MBTL1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9535494 | 0.81 | USP7 (0.43) | POLBMAPTSMN1; SMN2KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9539508 | 0.80 | L3MBTL1 (0.53) | L3MBTL1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9534137 | 0.79 | LMNA (0.50) | L3MBTL1POLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL9534810 | 0.79 | USP7 (0.51) | L3MBTL1POLBMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |