Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535539 | 0.86 | MAPK14 (0.42) | ALDH1A1KDM4EHPGDHTR7MAPK14 | |
| SCHEMBL9535499 | 0.84 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1LMNASLC22A2SLC22A1 | |
| Hydrochloric Acid SCHEMBL9539508 | 0.83 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1LMNASLC22A2SLC22A1 | |
| Diethylamine SCHEMBL9537391 | 0.83 | MAPK14 (0.41) | ALDH1A1KDM4EHPGDHTR7MAPK14 | |
| SCHEMBL9537015 | 0.80 | MAPK14 (0.48) | ALDH1A1CYP2C19KDM4EHPGDCYP3A4 | |
| SCHEMBL9537379 | 0.79 | ALDH1A1 (0.37) | ALDH1A1LMNAKDM4EHPGDMAPK14 | |
| SCHEMBL9535978 | 0.78 | MAPT (0.53) | ALDH1A1LMNATSHRMAPK1BLM | |
| SCHEMBL9538792 | 0.77 | MAPT (0.40) | ALDH1A1TSHRKMT2AKDM4EHPGD | |
| SCHEMBL2956109 | 0.77 | ALDH1A1 (0.71) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL9536752 | 0.77 | ALDH1A1 (0.43) | ALDH1A1CYP2C19KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |