Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537288 | 0.90 | SSTR5 (0.53) | TP53MAPTLMNASSTR5NR4A2 | |
| Hydrochloric Acid SCHEMBL9537481 | 0.88 | SLC6A9 (0.53) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL10547724 | 0.87 | SLC6A9 (0.55) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9537085 | 0.87 | SLC6A9 (0.58) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9535785 | 0.87 | SLC6A9 (0.58) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9535367 | 0.87 | SLC6A9 (0.58) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9537811 | 0.86 | SLC6A9 (0.60) | SLC6A9ENPP2TP53MAPTLMNA | |
| Oxalic Acid SCHEMBL10548563 | 0.85 | SSTR5 (0.51) | TP53MAPTLMNASSTR5NR4A2 | |
| Oxalic Acid SCHEMBL10548557 | 0.85 | SSTR5 (0.51) | TP53MAPTLMNASSTR5NR4A2 | |
| SCHEMBL9540167 | 0.85 | SLC6A9 (0.56) | SLC6A9ENPP2TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | disclosed |
| US-4695575-A | ANTIHISTAMINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1987-09-22 | — | — | US | disclosed |
| EP-0151826-A1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-08-21 | — | — | EP | disclosed |