Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535367 | 0.90 | SLC6A9 (0.58) | SLC6A9TP53MAPTENPP2LMNA | |
| SCHEMBL9537085 | 0.88 | SLC6A9 (0.58) | SLC6A9TP53MAPTENPP2LMNA | |
| SCHEMBL9535785 | 0.88 | SLC6A9 (0.58) | SLC6A9TP53MAPTENPP2LMNA | |
| Hydrochloric Acid SCHEMBL9537812 | 0.88 | SLC6A9 (0.52) | SLC6A9TP53MAPTENPP2LMNA | |
| SCHEMBL9537811 | 0.87 | SLC6A9 (0.60) | SLC6A9TP53MAPTENPP2LMNA | |
| SCHEMBL9538693 | 0.85 | SLC6A9 (0.52) | SLC6A9TP53MAPTENPP2LMNA | |
| SCHEMBL9535415 | 0.85 | SLC6A9 (0.55) | SLC6A9TP53MAPTENPP2LMNA | |
| SCHEMBL10547724 | 0.85 | SLC6A9 (0.55) | SLC6A9TP53MAPTENPP2LMNA | |
| SCHEMBL9535970 | 0.85 | SLC6A9 (0.55) | SLC6A9TP53MAPTENPP2LMNA | |
| SCHEMBL9537797 | 0.84 | RAB9A (0.57) | LMNAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | disclosed |