SCHEMBL95360

SCHEMBL95360

COc1ccc(O[C]=O)cc1OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.61
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
ALDH1A1 P00352 4/20 0.46
GAA P10253 1/20 0.46
ACHE P22303 1/20 0.45
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44
TUBA4A P68366 1/20 0.44
TUBB4B P68371 1/20 0.44
TUBB3 Q13509 1/20 0.44
TUBB2A Q13885 1/20 0.44
TUBB8 Q3ZCM7 1/20 0.44
TUBA3E Q6PEY2 1/20 0.44
TUBA1A Q71U36 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2089114 0.86 CA12 (0.65) CA2CA12CA1CA7CA9
SCHEMBL2090982 0.86 CA12 (0.65) CA2CA12CA1CA7CA9
SCHEMBL2089132 0.82 CA12 (0.41) CA2CA12CA1CA7CA9
SCHEMBL5444296 0.79 CA2 (0.61) CA2CA12CA1CA7CA9
SCHEMBL7013645 0.78 HIF1A (0.49) CA2CA12CA1CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL29350371 0.77 CA12 (1.00) CA2CA12CA1CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL481491 0.77 CA12 (1.00) CA2CA12CA1CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL27777905 0.77 CA12 (1.00) CA2CA12CA1CA7CA9
SCHEMBL2093197 0.77 ACHE (0.48) CA9ALDH1A1ACHETUBB4ATUBB
SCHEMBL27887830 0.76 CA2 (0.70) CA2CA12CA1CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116234813-A Assays and reagents for characterizing MHCI peptide binding 基因泰克公司 2023-06-06 CN claimed
US-5356914-A Cognition activators BEECHAM GROUP P.L.C. (GB) 1994-10-18 US claimed
EP-0552213-A1 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES BEECHAM GROUP PLC (GB) 1993-07-28 EP claimed
WO-1992006959-A1 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES BEECHAM GROUP PLC (GB) 1992-04-30 WO claimed
CN-117897617-A Assays and reagents for characterizing MHC II peptide binding 基因泰克公司 2024-04-16 CN disclosed
CN-108785305-A The heterocycle inhibitor of glutaminase 卡利泰拉生物科技公司 2018-11-13 CN disclosed
CN-107949387-A With glutamine ihibitors for treatment lung cancer 卡利泰拉生物科技公司 2018-04-20 CN disclosed
CN-107921031-A The method for giving glutamine enzyme inhibitor 卡利泰拉生物科技公司 2018-04-17 CN disclosed
EP-2719688-B1 Process for producing tetrazolyloxime derivatives NIPPON SODA CO (JP) 2016-07-20 EP disclosed
EP-2719686-B1 Process to halogenate a picoline derivative NIPPON SODA CO (JP) 2015-12-02 EP disclosed
EP-2719687-B1 Process to make a bromopicoline derivative NIPPON SODA CO (JP) 2015-09-16 EP disclosed
US-9018385-B2 Compound containing pyridine ring and method for producing halogenated picoline derivative and tetrazolyloxime derivative NIPPON SODA CO., LTD. (JP) 2015-04-28 US disclosed
EP-1695962-A1 CYCLIC AMINE DERIVATIVE HAVING HETEROARYL RING Sankyo Company, Limited (JP) 2006-08-30 EP disclosed
US-7030138-B2 Benzamidine derivatives SANKYO COMPANY, LIMITED (JP) 2006-04-18 US disclosed
WO-2006035954-A1 CARBOSTYRIL COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-04-06 WO disclosed
CN-1599640-A Biopolymer synthesis substrate and method for producing biopolymers MICRONAS GMBH (DE) 2005-03-23 CN disclosed
US-20040147555-A1 Benzamidine derivatives SANKYO COMPANY, LIMITED (JP) 2004-07-29 US disclosed
EP-1375482-A1 BENZAMIDINE DERIVATIVE Sankyo Company, Limited (JP) 2004-01-02 EP disclosed
US-5356914-A Cognition activators BEECHAM GROUP P.L.C. (GB) 1994-10-18 US disclosed
WO-1992006959-A1 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES BEECHAM GROUP PLC (GB) 1992-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147555-A1 Benzamidine derivatives F9, F7, F2 CA2 443/4885CA12 3204/4885CA1 2734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.