Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808816 | 0.92 | MEN1 (0.56) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL1760153 | 0.87 | NPC1 (0.44) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL3648358 | 0.86 | CTSK (0.49) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL20014854 | 0.84 | MTNR1A (0.61) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL16084764 | 0.82 | RIPK1 (0.53) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL1521024 | 0.82 | RIPK1 (0.53) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL4583816 | 0.81 | MEN1 (0.54) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL10318441 | 0.81 | MEN1 (0.50) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL10317783 | 0.81 | MEN1 (0.50) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL10317785 | 0.81 | MEN1 (0.50) | MEN1GAAKMT2ACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |