Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | BAX | Q07812 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272345 | 0.91 | PARP10 (0.58) | PARP10KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL9786679 | 0.91 | PARP10 (0.58) | PARP10KMT2AHPGDMAPTALDH1A1 | |
| Hydroquinone SCHEMBL7948998 | 0.86 | LMNA (0.60) | KMT2AESR1ESR2MEN1HPGD | |
| SCHEMBL1454951 | 0.86 | LMNA (0.60) | KMT2AESR1ESR2MEN1HPGD | |
| SCHEMBL9578958 | 0.84 | KMT2A (0.70) | PARP10KMT2AESR1ESR2MEN1 | |
| SCHEMBL11511385 | 0.83 | MMP1 (0.53) | PARP10KMT2AMEN1HPGDMAPT | |
| SCHEMBL9249310 | 0.83 | PARP10 (0.64) | PARP10KMT2ALTA4HNR1H2BAX | |
| SCHEMBL21786 | 0.83 | PARP10 (0.64) | PARP10KMT2ALTA4HNR1H2BAX | |
| SCHEMBL8671184 | 0.82 | PARP10 (0.69) | PARP10KMT2AESR1ESR2MEN1 | |
| SCHEMBL10486226 | 0.82 | MAPT (0.71) | PARP10KMT2AESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178184-B1 | PREPARATION OF AROMATIC CARBONYL COMPOUNDS | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5068447-A | Friedel-crafts preparation of aromatic ketones with an inoganic salt controlling agent | RAYCHEM CORPORATION (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0262919-B1 | PREPARATION OF ARYL CARBONYL COMPOUNDS | RAYCHEM LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |
| US-4898983-A | FRIEDEL-CRAFTS PROCESS; LEWIS ACIDS, BY-PRODUCT INHIBITION; ACID HALIDES, ACTIVE HYDROGEN AROMATIC COMPONENTS; CONTROLLING AGENTS | RAYCHEM LIMITED (GB) | 1990-02-06 | — | — | US | disclosed |
| US-4814508-A | Friedel-crafts preparation of aromatic ketones | RAYCHEM CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0262919-A2 | Preparation of aryl carbonyl compounds | RAYCHEM LIMITED (GB) | 1988-04-06 | — | — | EP | disclosed |
| EP-0178184-A1 | Preparation of aromatic carbonyl compounds | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | disclosed |