Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776435 | 0.88 | HTR1D (0.44) | DRD2HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL9534389 | 0.80 | HTR1D (0.46) | DRD2HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL10340261 | 0.80 | MTNR1A (0.49) | DRD2HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL9534218 | 0.79 | MTNR1A (0.52) | DRD2HTR1ADRD4ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9776624 | 0.78 | MTNR1A (0.51) | DRD2HTR1ADRD4ADRA1DADRA1A | |
| SCHEMBL9534913 | 0.77 | HTR1A (0.50) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL9776420 | 0.76 | HTR1A (0.53) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9776382 | 0.76 | HTR1A (0.49) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL9535224 | 0.76 | HTR1D (0.45) | DRD2HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL11021107 | 0.71 | HTR1A (0.56) | HTR1AHTR1DHTR1BMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332968-B1 | 1,3,4,5-Tetrahydrobenz[c,d]indoles | BAYER AG (DE) | 1993-06-02 | — | — | EP | disclosed |
| US-5021438-A | Having affinity for 5-hydroxytryptamine receptors; treating central nervous system and cardiovascular disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0332968-A1 | 1,3,4,5-Tetrahydrobenz[c,d]indoles | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |