Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | CEL | P19835 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3036894 | 1.00 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HPGDKDM5A | |
| SCHEMBL207351 | 1.00 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HPGDKDM5A | |
| SCHEMBL21831413 | 1.00 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HPGDKDM5A | |
| SCHEMBL866108 | 1.00 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HPGDKDM5A | |
| SCHEMBL21831588 | 1.00 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HPGDKDM5A | |
| SCHEMBL866938 | 1.00 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HPGDKDM5A | |
| SCHEMBL867290 | 1.00 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HPGDKDM5A | |
| SCHEMBL22524 | 0.97 | — | — | |
| SCHEMBL29156058 | 0.94 | CYP1A2 (0.50) | CYP1A2SIGMAR1EPHX1KDM5APHF8 | |
| SCHEMBL25313563 | 0.92 | SIGMAR1 (0.56) | CYP1A2SIGMAR1EPHX1KDM5APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4295 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207253-A1 | Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2024-06-27 | — | — | US | claimed |
| EP-4347597-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-10 | — | — | EP | claimed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | claimed |
| CN-116848094-A | Tertiary amine lipid compounds and uses thereof | 华南理工大学 | 2023-10-03 | — | — | CN | claimed |
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | claimed |
| WO-2022245951-A1 | INHIBITORS OF CDR1 FOR REVERSAL OF AZOLE DRUG RESISTANCE IN FUNGAL INFECTIONS | UNM RAINFOREST INNOVATIONS (US) | 2022-11-24 | — | — | WO | claimed |
| CN-110963952-B | Onium salt, resist composition and pattern forming method | 信越化学工业株式会社 | 2022-10-21 | — | — | CN | claimed |
| CN-111233786-B | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-11-26 | — | — | CN | claimed |
| CN-112300325-B | Optical film and method for producing the same | 聚纶材料科技（深圳）有限公司 | 2021-09-07 | — | — | CN | claimed |
| US-10955421-B2 | Detection of membrane proteins | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2021-03-23 | — | — | US | claimed |
| WO-1992003131-A1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES | G.D. SEARLE & CO. (US) | 1992-03-05 | — | — | WO | claimed |
| WO-1992000278-A1 | NOVEL IMMUNOSUPPRESSIVE COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1992-01-09 | — | — | WO | claimed |
| EP-0397427-A1 | Fluoro-amide derivatives having human leucocyte elastase inhibiting activity | ZENECA INC. (US) | 1990-11-14 | — | — | EP | claimed |
| WO-1989009205-A1 | METHODS FOR DEPLETION OF GLUTATHIONE | CORNELL RESEARCH FOUNDATION, INC. (US) | 1989-10-05 | — | — | WO | claimed |
| EP-0259752-A2 | Saccharide phosphates, their esters and method for their preparation | BAYER AG (DE) | 1988-03-16 | — | — | EP | claimed |
| EP-0238784-A2 | Process and system for preparing random copolymers having low vinyl contents | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1987-09-30 | — | — | EP | claimed |
| US-4672097-A | ANIONIC INITIATORS; SODIUM MAGNESIATE AND ORGANOLITHIUM COMPOUNDS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1987-06-09 | — | — | US | claimed |
| US-4537939-A | ORGANOLITHIUM INITIATOR WITH A TRI-N-HETEROCYCLIC PHOSPHINE OXIDE MODIFIER | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-08-27 | — | — | US | claimed |
| EP-0013914-B1 | PIPERAZINYL-IMIDAZO(1,2-A)PYRAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1982-12-15 | — | — | EP | claimed |
| US-3960906-A | INSECTICIDES | SANDOZ LTD. (CH) | 1976-06-01 | — | — | US | claimed |