SCHEMBL866108

SCHEMBL866108

[CH2]CCCC1CCCCCCCC1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
SIGMAR1 Q99720 4/20 0.52
EPHX1 P07099 1/20 0.36
HPGD P15428 1/20 0.34
KDM5A P29375 2/20 0.34
PHF8 Q9UPP1 2/20 0.34
KDM2A Q9Y2K7 2/20 0.34
KDM4C Q9H3R0 1/20 0.34
KDM4A O75164 1/20 0.34
CEL P19835 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95364 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL3036894 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL207351 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL21831413 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL21831588 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL866938 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL867290 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL22524 0.97
SCHEMBL29156058 0.94 CYP1A2 (0.50) CYP1A2SIGMAR1EPHX1KDM5APHF8
SCHEMBL25313563 0.92 SIGMAR1 (0.56) CYP1A2SIGMAR1EPHX1KDM5APHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597670-B1 WATER-SOLUBLE COMPOSITION, PRODUCTION METHOD FOR CURED PRODUCT THEREOF, AND CURED PRODUCT THEREOF, AND ACYL PHOSPHINATE ADEKA CORP (JP) 2024-07-10 EP disclosed
CN-118103209-A Composition for forming release layer, laminate, and method for producing laminate 日产化学株式会社 2024-05-28 CN disclosed
US-11958802-B2 Migration-resistant photopolymerization sensitizer KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-04-16 US disclosed
CN-113166554-B xanthene compounds 株式会社艾迪科 2023-12-12 CN disclosed
CN-110036343-B Water-soluble composition, pattern forming agent, method for producing cured product using same, and cured product 株式会社ADEKA 2023-06-13 CN disclosed
US-11649334-B2 Water-soluble composition, production method for cured product thereof, and cured product thereof, and acyl phosphinate ADEKA CORPORATION (JP) 2023-05-16 US disclosed
WO-2023074171-A1 RELEASE LAYER-FORMING COMPOSITION, LAMINATE, AND METHOD FOR MANUFACTURING LAMINATE 日産化学株式会社 2023-05-04 WO disclosed
WO-2023074169-A1 PRIMER LAYER-FORMING COMPOSITION, LAMINATE, AND METHOD FOR DECOMPOSING LAMINATE 日産化学株式会社 2023-05-04 WO disclosed
CN-114072474-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-04-28 CN disclosed
CN-115836100-A Polymerizable composition, cured product, and method for producing cured product 株式会社艾迪科 2023-03-21 CN disclosed
WO-2010142779-A1 ANTIFUNGAL 1,2,4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT BASF SE (DE) 2010-12-16 WO disclosed
US-20100204320-A1 PHARMACEUTICALS FOR XEROSIS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2010-08-12 US disclosed
US-7737182-B2 Pharmaceuticals for xerosis TAISHO PHARMACEUTICAL CO., LTD. (JP) 2010-06-15 US disclosed
US-7718701-B2 Prostaglandin, e.g., 1R,2R,3R,5R)-5-halo-2-[(1E,3S)-3-cycloalkyl-3-hydroxy-1-propenyl]-3-hydroxycyclopentyl]-(5Z)-5-alkenoic acids; treating in particular, symptoms of atopic dermatitis TAISHO PHARMACEUTICAL CO., LTD. (JP) 2010-05-18 US disclosed
EP-1527781-B1 ANTIPRURITIC AGENT TAISHO PHARMACEUTICAL CO LTD (JP) 2008-07-23 EP disclosed
US-20050192357-A1 Pharmaceuticals for xerosis Sato, Fumie 2005-09-01 US disclosed
EP-1527781-A1 ANTIPRURITIC AGENT TAISHO PHARMACEUTICAL CO., LTD (JP) 2005-05-04 EP disclosed
US-20050009917-A1 Antipruritic agent TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-01-13 US disclosed
US-6140338-A FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS BANYU PHARMACEUTICAL, CO., LTD. (JP) 2000-10-31 US disclosed
EP-0916668-A1 CHEMOKINE RECEPTOR ANTAGONISTS BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009917-A1 Antipruritic agent HRH2, HRH4, HRH1 CYP1A2 1723/4885SIGMAR1 220/4885EPHX1 312/4885
US-20100204320-A1 PHARMACEUTICALS FOR XEROSIS PTGDR, PTGDR2, PTGIR CYP1A2 899/4885SIGMAR1 797/4885EPHX1 841/4885
US-20050192357-A1 Pharmaceuticals for xerosis PTGDR, PTGDR2, PTGIR CYP1A2 993/4885SIGMAR1 694/4885EPHX1 881/4885
US-11958802-B2 Migration-resistant photopolymerization sensitizer F12, F10, PCNA CYP1A2 356/4885SIGMAR1 2719/4885EPHX1 1588/4885
US-11649334-B2 Water-soluble composition, production method for cured product thereof, and cured product thereof, and acyl phosphinate PHOSPHO1, ASS1, SGMS1 CYP1A2 2508/4885SIGMAR1 2309/4885EPHX1 2418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.