SCHEMBL3036894

SCHEMBL3036894

[CH2]CCCC1CCCCCCCCCCCCCC1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
SIGMAR1 Q99720 4/20 0.52
EPHX1 P07099 1/20 0.36
HPGD P15428 1/20 0.34
KDM5A P29375 2/20 0.34
PHF8 Q9UPP1 2/20 0.34
KDM2A Q9Y2K7 2/20 0.34
KDM4C Q9H3R0 1/20 0.34
KDM4A O75164 1/20 0.34
CEL P19835 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95364 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL207351 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL21831413 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL866108 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL21831588 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL866938 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL867290 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL22524 0.97
SCHEMBL29156058 0.94 CYP1A2 (0.50) CYP1A2SIGMAR1EPHX1KDM5APHF8
SCHEMBL25313563 0.92 SIGMAR1 (0.56) CYP1A2SIGMAR1EPHX1KDM5APHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365602-A1 COMPOUND FOR USE IN THE TREATMENT OF PROTOZOAL DISEASES AND PROCESS FOR PRODUCTION OF SAID COMPOUND QUADREL S.R.L. (IT) 2023-11-16 US disclosed
EP-4216960-A1 COMPOUND FOR USE IN THE TREATMENT OF PROTOZOAL DISEASES AND PROCESS FOR PRODUCTION OF SAID COMPOUND Quadrel S.r.l. (IT) 2023-08-02 EP disclosed
WO-2020204188-A1 PRODUCTION METHOD FOR CYCLIC OLEFIN COPOLYMER ポリプラスチックス株式会社 2020-10-08 WO disclosed
US-20200179914-A1 METHOD FOR PRODUCING CATALYST POLYPLASTICS CO., LTD. (JP) 2020-06-11 US disclosed
WO-2020071494-A1 METHOD FOR PRODUCING CYCLIC OLEFIN POLYMER ポリプラスチックス株式会社 2020-04-09 WO disclosed
EP-1957073-B1 MEDICINAL DRUG OTSUKA PHARMA CO LTD (JP) 2014-04-23 EP disclosed
US-8551999-B2 Heterocyclic compound and pharmaceutical composition thereof OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-10-08 US disclosed
EP-2612858-A1 STAT3/5 activation inhibitor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-07-10 EP disclosed
US-20120322807-A1 STAT3/5 ACTIVATION INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. 2012-12-20 US disclosed
US-20120238750-A1 AROMATIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. 2012-09-20 US disclosed
EP-2207773-A2 HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF Otsuka Pharmaceutical Co., Ltd. (JP) 2010-07-21 EP disclosed
US-20100004438-A1 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-01-07 US disclosed
EP-2089373-A1 STAT3/5 ACTIVATION INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-08-19 EP disclosed
WO-2009057811-A2 HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-05-07 WO disclosed
EP-1957073-A2 MEDICINAL DRUG OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-08-20 EP disclosed
WO-2008044667-A1 STAT3/5 ACTIVATION INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-04-17 WO disclosed
US-20070270422-A1 Aromatic Compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-11-22 US disclosed
WO-2007066784-A2 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-06-14 WO disclosed
EP-1773797-A2 AROMATIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-04-18 EP disclosed
WO-2006014012-A2 AROMATIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238750-A1 AROMATIC COMPOUND CBR1, CBR3, CYP1A1 CYP1A2 79/4885SIGMAR1 52/4885EPHX1 666/4885
US-20120322807-A1 STAT3/5 ACTIVATION INHIBITOR STAT3, JAK2, STAT1 CYP1A2 3133/4885SIGMAR1 549/4885EPHX1 4412/4885
US-20100004438-A1 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS ROS1, CBR1, CBR3 CYP1A2 979/4885SIGMAR1 21/4885EPHX1 894/4885
US-20230365602-A1 COMPOUND FOR USE IN THE TREATMENT OF PROTOZOAL DISEASES AND PROCESS FOR PRODUCTION OF SAID COMPOUND PIGO, PIGS, AGPS CYP1A2 1194/4885SIGMAR1 4672/4885EPHX1 615/4885
US-20070270422-A1 Aromatic Compounds COL1A1, COL2A1, COL14A1 CYP1A2 100/4885SIGMAR1 136/4885EPHX1 1267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.