Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533693 | 0.86 | ELANE (0.40) | NPC1RAB9AMAPTAPOBEC3GPDE7A | |
| SCHEMBL9533817 | 0.82 | TNKS (0.43) | PARP1HPGDKDM4EAKR1B1ALDH1A1 | |
| SCHEMBL10696216 | 0.80 | PARP1 (0.44) | NPC1RAB9AMAPTAPOBEC3GPDE7A | |
| SCHEMBL10696717 | 0.78 | PARP1 (0.43) | NPC1RAB9AMAPTAPOBEC3GPDE7A | |
| SCHEMBL9533229 | 0.77 | PARP1 (0.40) | NPC1RAB9AMAPTPARP1LMNA | |
| SCHEMBL9533336 | 0.74 | KDM4E (0.62) | NPC1RAB9AMAPTAPOBEC3GPDE7A | |
| SCHEMBL9536991 | 0.71 | CYP1A2 (0.50) | NPC1RAB9AMAPTAPOBEC3GPDE7A | |
| SCHEMBL9533044 | 0.69 | ELANE (0.40) | NPC1RAB9AMAPTPARP1LMNA | |
| SCHEMBL10696981 | 0.69 | PARP1 (0.38) | NPC1RAB9AMAPTAPOBEC3GPARP1 | |
| SCHEMBL11835611 | 0.65 | CDC25B (0.48) | NPC1RAB9AMAPTAPOBEC3GPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |