Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696717 | 0.86 | PARP1 (0.43) | PARP1MAPTNPC1RAB9AAPOBEC3G | |
| SCHEMBL10694328 | 0.86 | ELANE (0.42) | PARP1MAPTNPC1RAB9APDE7A | |
| SCHEMBL10695759 | 0.81 | CYP1A1 (0.43) | PARP1RXFP1KDM4EHPGDHSD17B10 | |
| SCHEMBL9536458 | 0.80 | NPC1 (0.45) | PARP1MAPTNPC1RAB9AAPOBEC3G | |
| SCHEMBL10696099 | 0.78 | PARP1 (0.44) | PARP1MAPTNPC1RAB9ARXFP1 | |
| SCHEMBL9533336 | 0.78 | KDM4E (0.62) | PARP1MAPTNPC1RAB9AAPOBEC3G | |
| SCHEMBL9533693 | 0.72 | ELANE (0.40) | PARP1MAPTNPC1RAB9AAPOBEC3G | |
| SCHEMBL10695331 | 0.72 | PDE7A (0.43) | PARP1MAPTNPC1RAB9APDE7A | |
| SCHEMBL9536991 | 0.69 | CYP1A2 (0.50) | PARP1MAPTNPC1RAB9AAPOBEC3G | |
| SCHEMBL9770665 | 0.69 | ELANE (0.42) | PARP1MAPTNPC1RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |