Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536155 | 0.89 | USP2 (0.42) | SLC6A9MAPK1HPGDPOLBALDH1A1 | |
| SCHEMBL10552371 | 0.88 | SLC6A9 (0.49) | SLC6A9LMNAMAPK1HPGDPOLB | |
| SCHEMBL9537181 | 0.87 | SLC6A9 (0.49) | SLC6A9LMNAMAPK1HPGDPOLB | |
| SCHEMBL9536805 | 0.85 | SLC6A9 (0.51) | SLC6A9LMNAMAPK1HPGDPOLB | |
| SCHEMBL9536208 | 0.84 | SLC6A9 (0.41) | SLC6A9LMNAMAPK1HPGDPOLB | |
| SCHEMBL9536826 | 0.84 | TP53 (0.51) | SLC6A9LMNAMAPK1HPGDPOLB | |
| SCHEMBL1152440 | 0.84 | HPGD (0.38) | LMNAMAPK1HPGDPOLBALDH1A1 | |
| SCHEMBL9538015 | 0.84 | SLC6A9 (0.65) | SLC6A9LMNAPOLBALDH1A1HSD17B10 | |
| SCHEMBL9537207 | 0.83 | SLC6A9 (0.47) | SLC6A9LMNAMAPK1HPGDPOLB | |
| SCHEMBL9535415 | 0.83 | SLC6A9 (0.55) | SLC6A9LMNAPOLBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | claimed |