Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535856 | 0.77 | PPARG (0.48) | ACHEALDH1A1AOC3KMT2A | |
| SCHEMBL10628649 | 0.72 | BCHE (0.31) | BCHEACHEREN | |
| SCHEMBL13085635 | 0.70 | KDM4E (0.42) | ALDH1A1ABCB11KMT2A | |
| SCHEMBL3040062 | 0.70 | PYCR1 (0.33) | ALDH1A1 | |
| SCHEMBL5486991 | 0.70 | AOC3 (0.49) | BCHEACHEAOC3 | |
| SCHEMBL15972314 | 0.69 | CYP3A4 (0.41) | BCHEACHEALDH1A1KMT2A | |
| SCHEMBL11175185 | 0.68 | ALDH1A1 (0.44) | ALDH1A1ABCB11FGFR1FGFR2FGFR4 | |
| SCHEMBL19009081 | 0.65 | ALDH1A1 (0.50) | ALDH1A1KMT2A | |
| SCHEMBL20340540 | 0.65 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL3183689 | 0.65 | ALDH1A1 (0.44) | ALDH1A1ABCB11AOC3FGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382629-B1 | Aminoalkoxyphenyl derivatives, process for their preparation and compositions containing them | SANOFI ELF (FR) | 1993-11-24 | — | — | EP | claimed |