Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430435 | 0.79 | PPARG (0.51) | PPARGPPARDPPARACYP1A2L3MBTL1 | |
| SCHEMBL9263967 | 0.78 | LTB4R (0.38) | PPARGPPARDPPARACYP1A2FDPS | |
| SCHEMBL9662716 | 0.77 | MAPT (0.49) | KDM4EL3MBTL1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL9536720 | 0.77 | BCHE (0.38) | KMT2AALDH1A1ACHEAOC3 | |
| SCHEMBL27345231 | 0.76 | CA1 (0.45) | PPARGPPARDPPARAPOLBTSHR | |
| Hydrochloric Acid SCHEMBL9661830 | 0.76 | MAPT (0.48) | KDM4EL3MBTL1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL10627153 | 0.74 | CYP3A4 (0.41) | TSHRCYP1A2L3MBTL1KMT2ACYP2C9 | |
| SCHEMBL28219379 | 0.73 | BCHE (0.48) | KDM4EPOLBCYP1A2L3MBTL1CYP2C9 | |
| SCHEMBL14160215 | 0.73 | ALDH1A1 (0.38) | PPARGPPARDPPARAPOLBL3MBTL1 | |
| SCHEMBL9436648 | 0.73 | ABCB1 (0.66) | TSHRCYP1A2L3MBTL1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382629-B1 | Aminoalkoxyphenyl derivatives, process for their preparation and compositions containing them | SANOFI ELF (FR) | 1993-11-24 | — | — | EP | claimed |